When I read this first as a young teenager, the depth of the writing and story were lost on me.  But the perfectly cast new film was a great excuse to revisit Dune, a novel so clearly a masterpiece of intelligence and deliberative thought that it stands above most of the science-fiction written in the 60 years since.

Two quick quotes to encapsulate the breadth of the book, and its encompassing of human thought and futurism with genuine philosophical maturity:
"There should be a word for memories that deny themselves."
"...[T]he highest function of ecology is the understanding of consequences."

Even George Lucas, whose original idea for midicholorians were mocked by fans, can be seen as the natural product of Frank Herbert's boundness and far less-hero minded work.  I'm gushing.  It's a brilliant and highly rewarding book.