The story revolves around Louisa Clark, a young woman who takes on a job as a caregiver for Will Traynor, a wealthy and successful man who is paralyzed from the neck down after a tragic accident.

Initially, Louisa and Will clash due to their differences in personalities and outlooks on life. However, as they spend more time together, they form an unlikely bond and develop a deep connection. Louisa is determined to show Will that life is still worth living and tries to broaden his horizons by introducing him to new experiences.

The novel explores themes of love, self-discovery, and the right to make choices about one's own life. As Louisa and Will's relationship deepens, they both learn valuable lessons about finding happiness, taking risks, and appreciating the beauty of everyday moments.

"Me Before You" is an emotional and thought-provoking story that examines complex moral and ethical dilemmas. It delves into the challenges of living with a disability and tackles the sensitive topic of assisted suicide. The novel raises important questions about quality of life, personal autonomy, and the power of human connection.